ADRB3 Gene Trp64Arg Polymorphism and Essential Hypertension: A Meta-Analysis Including 9,555 Subjects
نویسندگان
چکیده
1 Department of Geriatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 2 Clinical Research Center, First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 3 Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 4 Department of Intensive Care Unit, Baoding First Central Hospital, Baoding, China, 5 Department of Geriatrics, Nanjing General Hospital, Nanjing, China, 6 Department of Physiology, University of Cincinnati, Cincinnati, OH, United States
منابع مشابه
An association between TRP64ARG polymorphism of the B3 adrenoreceptor gene and some metabolic disturbances
BACKGROUNDS B3 adrenoreceptors (ADRB3) are abundant in adipose tissue and play the role in its metabolism and lipolysis. Some variants of the ADRB3 gene may predispose subjects for the development obesity and metabolic abnormalities in the setting of modern sedentary lifestyle. ADRB3 gene polymorphism association with metabolic disturbances has never been studied before in the ethnic Kyrgyz pop...
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This meta-analysis was implemented to test the association of a missense mutation, Trp64Arg, in β3-adrenoreceptor-encoding gene (ADRB3) with both hypertension risk and blood pressure (BP) changes. A systematic search of three publicly-available databases was launched to look for articles published as of December 2016. Qualification appraisal and data extraction were independently done by two re...
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In this study, allele and genotype frequencies of the ADRB1 Arg389Gly (rs1801253), ADRB2 Gly16Arg (rs1042713) and Gln27Glu (rs1042714), and ADRB3 Trp64Arg (rs4994) variations were compared in the following three groups of Spanish (Caucasian) men: (1) world-class endurance athletes (E; runners and cyclists, n=100), (2) elite power athletes (P; sprinters, jumpers and throwers, n=53) and (3) non-a...
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BACKGROUND The β3-adrenoceptor (ADRB3) gene Trp64Arg polymorphism has been shown to be associated with obesity as well as type 2 diabetes and cardiovascular disease. The incidence of overweight and the risks of type 2 diabetes and cardiovascular disease are also increased in major depression and schizophrenia. We hypothesized that the Trp64Arg polymorphism may be associated with increased risk ...
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This research was designed to analyze the possible associations of Arg389Gly ADRB1 and Trp64Arg ADRB3 polymorphisms in children with obesity. A cross-sectional study included 1,046 school-age Mexican participants (6-12 years old) from the cities of San Luis PotosÍ and León. Children were classified as non-obese or obese according to their body mass index (BMI) percentile; obese children had a B...
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تاریخ انتشار 2018